933474-68-1

Basic information

• Product Name: N-(2-amino-6-hydroxy-phenyl)-N'-butyl-oxalamide
• Synonyms: N-(2-amino-6-hydroxy-phenyl)-N'-butyl-oxalamide
• CAS NO: 933474-68-1
• Molecular Weight: 251.285
• Mol File: 933474-68-1.mol

Chemical Properties

• CAS DataBase Reference: N-(2-amino-6-hydroxy-phenyl)-N'-butyl-oxalamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-amino-6-hydroxy-phenyl)-N'-butyl-oxalamide(933474-68-1)
• EPA Substance Registry System: N-(2-amino-6-hydroxy-phenyl)-N'-butyl-oxalamide(933474-68-1)

Safety Data

• Hazardous Substances Data: 933474-68-1(Hazardous Substances Data)

Upstream product

• 89521-54-0 2-(benzyloxy)-6-nitroaniline 
• 933474-67-0 N-(2-benzyloxy-6-nitro-phenyl)-oxalamic acid ethyl ester 

Downstream Products

• 910026-61-8 7-hydroxy-1H-benzimidazole-2-carboxylic acid 

Relevant articles and documents

Selective NR1/2B N-methyl-D-aspartate receptor antagonists among indole-2-carboxamides and benzimidazole-2-carboxamides

(4-Benzylpiperidine-1-yl)-(6-hydroxy-1H-indole-2-yl)-methanone (6a) derived from (E)-1 -(4-benzylpiperidin-1-yl)-3-(4-hydroxy-phenyl)-propenone (5) was identified as a potent NR2B subunit-selective antagonist of the NMDA receptor. To establish the structu

Benzimidazole-2-carboxamides as novel NR2B selective NMDA receptor antagonists

A novel series of benzimidazole-2-carboxamide derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of some structural elements, like H-bond donor groups placed on the benzimidazole skeleton and the substitution pattern of the piperidine ring, on the biological activity was studied. Compound 6a showed excellent analgetic activity in the mouse formalin test following po administration.