93355-96-5Relevant academic research and scientific papers
COMPOUNDS CONTAINING A SULFONIC GROUP AS KAT INHIBITORS
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Paragraph 0382; 0383; 0384; 0385; 0386; 0387, (2018/06/21)
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
Synthesis of Some Triazole, Tetrazole, and Tetrazine Derivatives from N-β-Naphthalenesulfonylbenzohydrazidoyl Chlorides
Hassaneen, Hamdi M.,Fahmi, Abdelgawad A.,Abdelhamid, Hyam,Yassin, Ahmady A.,Shawali, Ahmad S.
, p. 797 - 800 (2007/10/02)
A series of N-β-naphthalenesulfonylbenzohydrazidoyl chlorides 8a-d has been prepared by the action of thionyl chloride on the corresponding hydrazides 7a-d.Treatment of 8 with triethylamine and morpholine afforded the tetrazines 10 and the amidrazones 11 respectively.Acid hydrolysis of 11 yielded the hydrazides 7.Reaction of 8 with phenylhydrazine gave 3,5-diaryltetrazoles 14.However, reaction of 8 with aroylhydrazines yielded 3,5-diaryl-4-β-naphthalenesulfonylamino-4H-1,2,4-triazoles 15.The structures of the products were assigned upon the basis of their spectra, elemental analyses and alternative synthesis whereever possible.
