933702-16-0 Usage
General Description
6-Chloropyrimidine-4-carbaldehyde is a chemical compound with the molecular formula C6H3ClN2O. It is a derivative of pyrimidine, which is a six-membered heterocyclic ring containing nitrogen atoms. 6-chloropyriMidine-4-carbaldehyde is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also utilized in the production of various fine chemicals and is a key building block in the pharmaceutical industry. Its functional group allows it to undergo various chemical reactions, making it a versatile compound with numerous applications in organic synthesis. Additionally, it is important to handle and store this compound with caution, as it may pose hazards to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 933702-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,3,7,0 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 933702-16:
(8*9)+(7*3)+(6*3)+(5*7)+(4*0)+(3*2)+(2*1)+(1*6)=160
160 % 10 = 0
So 933702-16-0 is a valid CAS Registry Number.
933702-16-0Relevant articles and documents
Pyrimidinylimidazole inhibitors of CSBP/P38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes
Adams, Jerry L.,Boehm, Jeffrey C.,Kassis, Shouki,Gorycki, Peter D.,Webb, Edward F.,Hall, Ralph,Sorenson, Margaret,Lee, John C.,Ayrton, Andrew,Griswold, Don E.,Gallagher, Timothy F.
, p. 3111 - 3116 (2007/10/03)
Pyrimidine analogs of the pyridinylimidazole class of CSBP/p38 kinase inhibitors were prepared in an effort to reduce the potent inhibition of hepatic cytochrome P450 observed for the pyridinyl compounds. The substitution of pyrimidin-4-yl, 2-methoxypyrimidin-4-yl, or 2- methylaminopyrimidin-4-yl for pyridin-4-yl effectively dissociates CSBP/p38 kinase from P450 inhibition for this series and furthermore achieves an increase in oral activity.