933774-11-9Relevant academic research and scientific papers
New synthesis of N-substituted benz[g]isoquinoline-3,5,10(2H)-triones
Jacobs, Jan,Claessens, Sven,Kesteleyn, Bart,Huygen, Kris,De Kimpe, Norbert
, p. 2503 - 2510 (2007/10/03)
Various N-substituted benz[g]isoquinoline-3,5,10(2H)-triones 7 were prepared starting from vitamin K3 (menadione) 9. The key steps involve substitution of a benzylic bromide by a primary amine and intramolecular condensation across the ester mo
