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Usage

Uses

Used in Organic Synthesis:
(4-(4-(TrifluoroMethyl)phenoxy)phenyl)Methanol is used as a building block for the synthesis of complex organic molecules, taking advantage of its unique structure and reactivity.
Used in Pharmaceutical Research:
(4-(4-(TrifluoroMethyl)phenoxy)phenyl)Methanol is used as a starting material in the development of new drugs, particularly due to its trifluoromethyl group, which is valuable for medicinal chemistry and the development of bioactive molecules.
Used in Medicinal Chemistry:
(4-(4-(TrifluoroMethyl)phenoxy)phenyl)Methanol is used as a key intermediate in the synthesis of various bioactive molecules, contributing to the advancement of drug discovery and development.

Upstream product

• 78161-82-7 4-[4-(trifluoromethyl)phenoxy]benzoic acid 
• 402-45-9 4-hydroxybenzotrifluoride 
• 459-57-4 4-fluorobenzaldehyde 
• 1128268-16-5 Methyl 4-[4-(trifluoromethyl)phenoxy]benzoate 

Downstream Products

• 1305170-07-3 C₃₂H₂₃F₆N₃O₄ 
• 117114-01-9 4-(4'-trifluoromethylphenoxy)-benzyl bromide 

Relevant academic research and scientific papers

Synthesis and Structure-Activity Relationships for Extended Side Chain Analogues of the Antitubercular Drug (6 S)-2-Nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5 H -imidazo[2,1- b ][1,3]oxazine (PA-824)

Novel extended side chain nitroimidazooxazine analogues featuring diverse linker groups between two aryl rings were studied as a potential strategy to improve solubility and oral activity against chronic infection by Mycobacterium tuberculosis. Both lipop

2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS

Disclosed are compounds of formula (I) wherein R1 and R2 are independently selected from hydrogen, halo, CF3, C1-4alkyl and allyl; Y represents (II), (III), (IV) or (V) wherein R3 represents CF3 or C1-4alkyl; and R3a represents CF3 or C1-4alkyl.

SOLUBLE GUANYLATE CYCLASE ACTIVATORS

A compound having the structure useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, angina pectoris, thromboses, restenoses, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver in a human or animal patient.

4-OXY-N-[1 ,3,4]-THIADIAZOL-2-YL-BENZENE SULFONAMIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

The invention relates to 4-oxy-N-[1 ,3,4]-thiadiazol-2-yl-benzene sulfonamides and to their physiologically acceptable salts and physiologically functional derivatives showing PPARalpha, PPARdelta and PPARgamma agonist activity. What is described are comp