933787-91-8

Upstream product

• 928205-93-0 2,5-dichloro-4-methyl-benzo[c][2,7]naphthyridine 
• 123-30-8 4-amino-phenol 
• 933787-90-7 2-Chlor-4-methyl-N-(4-methoxyphenyl)benzo[c][2,7]naphthyridin-5-yl-amin 
• 104-94-9 4-methoxy-aniline 

Relevant academic research and scientific papers

Benzo[c][2,7]naphthyridine-5-yl-arylamines - Phenol Mannich bases of the amodiaquine-, cycloquine- and pyronaridine-type

2,5-Dichloro-4-methyl-benzo[c][2,7]naphthyridine (1) reacted with aromatic amines selectively by substitution at the 5-position to yield the amidines 2. The 4-aminophenol 2c could also be synthesized by cleavage of the ether 2b. The structure of 2c was pr