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4-Amino-2-(propylthio)-5-pyrimidinecarbonitrile is a substituted pyrimidine compound characterized by the presence of an amino group, a propylthio group, and a carbonitrile group attached to its pyrimidine ring. This organic molecule serves as a crucial intermediate in the synthesis of various chemical compounds, particularly Thiamine (T344185) analogues.

933949-26-9

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933949-26-9 Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-2-(propylthio)-5-pyrimidinecarbonitrile is used as a key intermediate in the synthesis of Thiamine (T344185) analogues for the development of potential therapeutic agents. Thiamine, also known as vitamin B1, plays a vital role in energy production and cellular metabolism. The analogues synthesized using this intermediate may exhibit modified properties or enhanced efficacy, offering new treatment options for various health conditions.
Additionally, due to its unique structural features, 4-Amino-2-(propylthio)-5-pyrimidinecarbonitrile may also be utilized in the development of other pharmaceutical compounds with diverse applications, such as antimicrobial, antiviral, or anticancer agents. Its potential use in these areas would be based on its ability to form specific interactions with biological targets, leading to the modulation of cellular processes and the inhibition of disease progression.

Check Digit Verification of cas no

The CAS Registry Mumber 933949-26-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,3,9,4 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 933949-26:
(8*9)+(7*3)+(6*3)+(5*9)+(4*4)+(3*9)+(2*2)+(1*6)=209
209 % 10 = 9
So 933949-26-9 is a valid CAS Registry Number.

933949-26-9Upstream product

933949-26-9Downstream Products

933949-26-9Relevant academic research and scientific papers

Synthesis and anticancer activity of novel 2-alkylthio-4-amino-5-(thiazol-2-YL)pyrimidines

Bunev, Alexander S.,Khochenkov, Dmitry A.,Khochenkova, Yulia A.,Machkova, Yulia S.,Varakina, Elena V.,Gasanov, Rovshan E.,Troshina, Marina A.,Avdyakova, Olga S.

, p. 2521 - 2527 (2021)

A series of new fist-time synthesized of thiazolyl-substituted 4-aminopyrimidine was obtained on the basis of a two-stage process including thioamidation of 4-amino-5-cyanopyrimide followed by one-pot acylation and Hantzsch synthesis in good yield (52–77%

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