933989-07-2

Upstream product

• 134653-70-6 ethyl 2-[(dimethylamino)methylene]-3-oxobutanoate 

Downstream Products

• 933989-08-3 [3-({[2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carbonyl]-amino}-methyl)-benzyl]-carbamic acid tert-butyl ester 
• 1068970-09-1 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid pyrrolo[2,3-b]pyridin-1-ylamide 
• 1068970-08-0 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid pyrrolo[3,2-b]pyridin-1-ylamide 
• 1068970-28-4 2-(3-fluorophenyl)-4-methylpyrimidine-5-carboxylic acid (5-fluoroindol-1-yl)amide 
• 1068969-98-1 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (5-methanesulfonyl-indol-1-yl)-amide 
• 1068970-85-3 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (3-chloro-5-fluoro-indol-1-yl)-amide 
• 1068968-60-4 2-(3-fluoro-phenyl)-4-methylpyrimidine-5-carboxylic acid (3-cyano-5-fluoro-indol-1-yl)-amide 
• 1068975-17-6 5-fluoro-1-{[2-(3-fluorophenyl)-4-methylpyrimidine-5-carbonyl]amino}-1H-indole-3-sulfonyl chloride 
• 1068975-16-5 5-fluoro-1-{[2-(3-fluorophenyl)-4-methylpyrimidine-5-carbonyl]amino}-1H-indole-3-sulfonic acid 
• 1068970-87-5 5-fluoro-1-{[2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carbonyl]-amino}-1H-indole-3-carboxylic acid amide 
• 1068968-63-7 2-(3-fluoro-phenyl)-4-methylpyrimidine-5-carboxylic acid [5-fluoro-3-(1H-tetrazol-5-yl)-indol-1-yl]-amide 
• 1068968-57-9 2-(3-fluoro-phenyl)-4-methylpyrimidine-5-carboxylic acid [5-fluoro-3-(2-hydroxy-2-methyl-propyl)-indol-1-yl]-amide 
• 1068970-92-2 2-(5-fluoro-1-{[2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carbonyl]-amino}-1H-indol-3-yl)-2-methyl-propionic acid 
• 1068967-94-1 2-(3-fluoro-phenyl)-4-methyl-pyrimidine-5-carboxylic acid (5-fluoro-2-methyl-indol-1-yl)amide 

Relevant academic research and scientific papers

PYRIMIDINE HYDRAZIDE COMPOUNDS AS PGDS INHIBITORS

This invention is directed to a compound wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or

PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS

This invention is directed to a compound of formula (I): wherein R1, R2, R3 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).