934-61-2Relevant academic research and scientific papers
(13)C magnetic resonance studies. 124. Preparative ring expansions of bicyclic ketones by homoketonization of cylopropoxide analogs
Patel, Vijay,Ragauskas, Arthur J.,Stothers, J. B.
, p. 1440 - 1449 (2007/10/02)
Homoketonization of some readily prepared cyclopropoxides provides a new synthetic method for ring expansion of the and ring systems.Cyclopropanation of the trimethylsilyl enol ethers derived from a variety of polycyclic ketones affords the required cyclopropyl silyl ethers, which may be ketonized directly or hydrolyzed to the corresponding cyclopropanols before ketonization.The results for fourteen examples serve to define the scope of the ring expansion process, and the silyl enol ethers, cyclopropyl silyl ethers, and most of the corresponding cyclopropanols have been characterized by (13)Cmr.The stereochemistry of the ketonization leading to ring expansion has been established by deuterium labelling experiments.
A new preparative ring expansion for bicyclic ketones. Homoketonization of cyclopropoxide analogs
Hoyano, Yumiko,Patel Vijay,Stothers, J. B.
, p. 2730 - 2732 (2007/10/02)
Homoketonization of some readily prepared cyclopropoxides affords a new synthetic method for ring expansion of the and ring systems.
