934021-52-0Relevant articles and documents
Synthesis of (2S,2′S)-bimorpholine N,N′-quaternary salts as chiral phase transfer catalysts
Lippur, Kristin,Kanger, Tonis,Kriis, Kadri,Kailas, Tiiu,Mueuerisepp, Aleksander-Mati,Pehk, Tonis,Lopp, Margus
, p. 137 - 141 (2007)
(2S,2′S)-Bimorpholine was synthesized starting from (R,R)-tartaric acid ester acetal in six steps in 50% of the total yield. Key steps include: cyanide catalyzed amidation and one-step cyclization with p-toluenesulfonyl imidazole. Derivatization of N,N′-d