93413-57-1

Basic information

• Product Name: (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine
• Synonyms: (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine;-1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine;Dehydro Venlafaxine;Venlafaxine EP IMpurity F
• CAS NO: 93413-57-1
• Molecular Formula: C17H25NO
• Molecular Weight: 259.39
• Product Categories: Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 93413-57-1.mol

Chemical Properties

• Boiling Point: 367.5°C at 760 mmHg
• Flash Point: 108.4°C
• Appearance: /
• Density: 1.007g/cm³
• Vapor Pressure: 1.36E-05mmHg at 25°C
• Refractive Index: 1.539
• Storage Temp.: Amber Vial, -20°C Freezer
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine(93413-57-1)
• EPA Substance Registry System: (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine(93413-57-1)

Safety Data

• Hazardous Substances Data: 93413-57-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is used as an intermediate in the synthesis of various pharmaceutical compounds, including antidepressant drugs such as Venlafaxine. It plays a crucial role in the production of Dehydrovenlafaxine, a metabolite of Venlafaxine, which is a selective serotonin noradrenaline reuptake inhibitor used for treating depression and other mood disorders.
Used in Research and Development:
(+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is also used as a research compound in the development of new drugs and therapies. Its unique structure and properties make it a valuable tool for studying the interactions between molecules and biological systems, potentially leading to the discovery of novel treatments for various diseases and conditions.
Used in Quality Control and Impurity Testing:
As a degradation product and impurity of Venlafaxine, (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine is used in quality control and impurity testing of pharmaceutical products. Ensuring the purity and safety of medications is essential for maintaining the efficacy and reliability of treatments, and (+/-)--1-Cyclohexen-1-yl-4-methoxy-N,N-dimethylbenzeneethanamine plays a role in monitoring and controlling the presence of impurities in Venlafaxine and its related products.

InChI:InChI=1/C17H25NO/c1-18(2)13-17(14-7-5-4-6-8-14)15-9-11-16(19-3)12-10-15/h7,9-12,17H,4-6,8,13H2,1-3H3

Upstream product

• 93413-69-5 1-[2-dimethylamino-1-(4-methoxyphenyl)ethyl]cyclohexanol 

Relevant articles and documents

Impurity profile study of venlafaxine hydrochloride, an antipsychotic drug substance

Venlafaxine hydrochloride is a phenyl ethylamine derivative, used for the treatment of depression. During the process development of venlafaxine hydrochloride, six process-related potential impurities were detected in high-performance liquid chromatograph

2-PHENYL-2-(1-HYDROXYCYCLOALKYL OR 1-HYDROXYCYCLOALK-2-ENYL)ETHYLAMINE DERIVATIVES

This invention provides a group of hydroxycycloalkanephenethyl amine antidepressant derivatives of the following structural formula: STR1 in which A is a moiety of the formula STR2 where the dotted line represents optional unsaturation;R 1 is hydrogen or alkyl;R 2 is alkyl;R. sub.4 is hydrogen, alkyl, formyl or alkanoyl;R 5 and R 6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl or, taken together, methylenedioxy;R. sub.7 is hydrogen or alkyl; andn is 0, 1, 2, 3 or 4;or a pharmaceutically acceptable salt thereof.