93415-08-8

Upstream product

• 90841-55-7 benzyl 3-bromopropionate 
• 141-76-4 3-iodopropanoic acid 
• 100-51-6 benzyl alcohol 
• 6282-07-1 3-chloro-propionic acid benzyl ester 

Downstream Products

• 10276-85-4 benzyl caprylate 
• 855990-04-4 (2R,4R)-3-(2-tert-butyl-4-carboxymethyl-5-oxo-[1,3]-dioxolan-4-yl) propionic acid benzyl ester 
• 93399-06-5 7-[4-(2-benzyloxycarbonylethyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid hydriodide 
• 104108-29-4 prenyl tributylstannane 
• 108957-11-5 benzyl 6-methylhept-5-enoate 

Relevant academic research and scientific papers

A facile method for synthesis of (R)-(-)- and (S)-(+)-homocitric acid lactones and related α-hydroxy dicarboxylic acids from D- or L-malic acid

We report here a simple and convenient route for the stereoselective synthesis of (R)-(-)- and (S)-(+)-homocitric acid lactones, which play very important roles in biochemistry. The method involves only three steps, starting from the readily available met

Stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu

The stereoselective synthesis of a set of two functionalized (E)-alkene dipeptide isosteres of L-amino acid-L-Glu and L-amino acid-D-Glu was carried out. The treatment of N-arylsulfonyl-γ,δ-cis- or -trans-γ,δ-epimino (E)-α,β-enoates with HCl-1,4-dioxane afforded regio- and stereo-selective ring-opened products. The ring-opening reaction provided a useful method for the stereoselective synthesis of a set of diastereomeric (L-Xaa, L-Glu)-type and (L-Xaa, D-Glu)-type (E)-alkene dipeptide isosteres (EADI) from a single substrate of γ,δ-epimino (E)-α,β-enoate using organozinc-copper reagents.

Bactericidal agents

A method of combating plant-pathogenic bacteria, comprising applying to the bacteria or to a bacteria habitat a bactericidally effective amount of a cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid derivative of the formula STR1 in which A represents straight-chain or branched alkylene with 1 to 6 carbon atoms or a >C=CH-- radical, R1 represents alkoxycarbonyl with 1 to 6 carbon atoms in the alkyl part, benzyloxycarbonyl, carboxyl, optionally substituted carbamoyl, cyano or dialkoxyphosphonyl or alkylsulphonyl with 1 to 4 carbon atoms in the alkyl part, and R2 represents hydrogen, alkoxycarbonyl with 1 to 6 carbon atoms in the alkyl part, benzyloxycarbonyl, optionally substituted carbamoyl, cyano, chlorine, acetyl, alkyl with 1 to 3 carbon atoms or phenyl, or R1 and R2, together with the carbon atom which they substitute, can also form a 2-oxo-tetrahydrofuryl ring, R3, R4, R5 and R6 can be identical or different and represent hydrogen, methyl, ethyl or n- or i-propyl and X represents hydrogen, halogen or nitro, or an acid addition salt, alkali metal salt, alkaline earth metal salt, heavy metal salt or hydrate thereof. The heavy metal salts are new.

Quinolone acids and antibacterial agents containing these compounds

The invention relates to quinolone carboxylic acids of the formula (I) as defined herein, pharmaceutical compositions containing said quinolone carboxylic acids and the use of said compounds and compositions for treatment of bacterial infection. Also included in the invention are process for the manufacture of the active quinolone carboxylic acids.