93418-24-7

Basic information

• Product Name: 4-chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
• Synonyms: 4-chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide
• CAS NO: 93418-24-7
• Molecular Formula: C₁₂H₁₀ClN₃O
• Molecular Weight: 247.6803
• Mol File: 93418-24-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide(93418-24-7)
• EPA Substance Registry System: 4-chloro-N'-(1H-pyrrol-2-ylmethylene)benzohydrazide(93418-24-7)

Safety Data

• Hazardous Substances Data: 93418-24-7(Hazardous Substances Data)

Upstream product

• 1003-29-8 2-pyrrole aldehyde 
• 536-40-3 4-chlorobenzoic acid hydrazide 

Relevant articles and documents

Synthesis and structure of arene ruthenium(II) complexes: One-pot catalytic approach to synthesis of bioactive quinolines under mild conditions

Efficient catalytic one-step synthesis of substituted quinoline derivatives using newly synthesized Ru(II) half-sandwich complexes of the type [Ru(η6-p-cymene)Cl(L)] (L = pyrrole-2-aldehydehydrazones) under mild conditions is described. The synthesized complexes exhibit excellent catalytic activity towards the coupling of 2-amino alcohol with functionalized ketones and secondary alcohols in the optimal conditions and afforded the corresponding quinoline derivatives. The synthetic pathway proceeds with high atom efficiency via a sequence of acceptorless dehydrogenation and condensation steps. The maximum isolated yield of the product obtained was up to 97% using 0.3?mol% of catalyst loading for 5?h. These findings significantly advance the scope of the synthesis of bioactive heterocyclic compounds from readily available starting materials.