934187-40-3

Basic information

• Product Name: 1-(4-chloro-2,6-dimethylphenyl)-5-[(2,4-difluorophenyl)acetyl]-2(1H)-pyridinone
• CAS NO: 934187-40-3
• Molecular Weight: 387.813
• Mol File: 934187-40-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-chloro-2,6-dimethylphenyl)-5-[(2,4-difluorophenyl)acetyl]-2(1H)-pyridinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chloro-2,6-dimethylphenyl)-5-[(2,4-difluorophenyl)acetyl]-2(1H)-pyridinone(934187-40-3)
• EPA Substance Registry System: 1-(4-chloro-2,6-dimethylphenyl)-5-[(2,4-difluorophenyl)acetyl]-2(1H)-pyridinone(934187-40-3)

Safety Data

• Hazardous Substances Data: 934187-40-3(Hazardous Substances Data)

Upstream product

• 887307-17-7 5-[(2,4-difluorophenyl)acetyl]-2H-pyran-2-one 
• 24596-18-7 4-chloro-2,6-dimethylaniline 

Downstream Products

• 934187-41-4 5-[bromo(2,4-difluorophenyl)acetyl]-1-(4-chloro-2,6-dimethylphenyl)-2(1H)-pyridinone 
• 934188-45-1 (2Z)-1-[1-(4-chloro-2,6-dimethylphenyl)-6-oxo-1,6-dihydro-3-pyridinyl]-2-(2,4-difluorophenyl)-1,2-ethanedione 2-oxime 
• 934188-42-8 1-(4-chloro-2,6-dimethylphenyl)-5-[(1Z)-2-(2,4-difluorophenyl)-N-hydroxyethanimidoyl]-2(1H)-pyridinone 

Relevant articles and documents

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PHARMACEUTICAL APPLICATION THEREOF

It is intended to provide a compound represented by the general formula (I): (I) (wherein all the symbols are as defined in the description) which has a p38 MAP kinase inhibitory activity, a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. The compound of the invention is useful for preventing or treating a disease in which the abnormal production of a cytokine such as an inflammatory cytokine or a chemokine or overreaction to them is considered to be involved in the cause and aggravation of pathological conditions, in other words, an inflammatory disease, a respiratory disease, a cardiovascular disease, a central nervous system disease or the like, which is a cytokine-mediated disease.