934347-95-2

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 16817-43-9 5-Bromo-2-chloroanisole 

Downstream Products

• 934347-98-5 4-(4-chloro-3-methoxy-phenyl)-piperidin-4-ol hydrochloride 

Relevant academic research and scientific papers

PREPARATION OF A CHK1 INHIBITOR COMPOUND

The invention provides a novel synthetic route for the preparation of the Chk-1 inhibitor compound; also provided by the invention is a novel process for the preparation of the synthetic intermediate of formula (11); as well as novel process intermediates

MONOCYCLIC AND BICYCLIC COMPOUNDS AND METHODS OF USE

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Piperidine derivatives and methods of use

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment