934391-82-9

Basic information

• Product Name: 4-(5-fluoro-2-methoxy-phenyl)-4-methyl-2-oxo-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide
• CAS NO: 934391-82-9
• Molecular Weight: 385.392
• Mol File: 934391-82-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(5-fluoro-2-methoxy-phenyl)-4-methyl-2-oxo-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-fluoro-2-methoxy-phenyl)-4-methyl-2-oxo-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide(934391-82-9)
• EPA Substance Registry System: 4-(5-fluoro-2-methoxy-phenyl)-4-methyl-2-oxo-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide(934391-82-9)

Safety Data

• Hazardous Substances Data: 934391-82-9(Hazardous Substances Data)

Upstream product

• 65399-05-5 5-amino-3H-isobenzofuran-1-one 
• 452-08-4 2-bromo-4-fluoro-1-methoxybenzene 
• 71313-97-8 2-(5-fluoro-2-methoxyphenyl)propan-2-ol 
• 566920-34-1 4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-oxopentanoic acid ethyl ester 
• 217196-31-1 4-(5-fluoro-2-methoxyphenyl)-4-methyl-2-oxopentanoic acid 

Downstream Products

• 566920-43-2 2-cyclohexylmethyl-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methylpentanoic acid (1-oxo-1,3-dihydroisobenzofuran-5-yl)amide 
• 566920-55-6 4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(2-methylbenzyl)pentanoic acid (1-oxo-1,3-dihydroisobenzofuran-5-yl)amide 
• 566920-89-6 2-(3,5-dimethylbenzyl)-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methylpentanoic acid (1-oxo-1,3-dihydroisobenzofuran-5-yl)amide 
• 271587-28-1 5-[4-(5-fluoro-2-hydroxyphenyl)-2-hydroxy-4-methyl-2-trifluoromethyl-valeroylamino]-phthalide 
• 566920-85-2 4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(3-methylbenzyl)pentanoic acid (1-oxo-1,3-dihydroisobenzofuran-5-yl)amide 
• 566920-36-3 2-benzyl-4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methylpentanoic acid (1-oxo-1,3-dihydroisobenzofuran-5-yl)amide 
• 217193-92-5 5-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-trifluoromethyl-valeroylamino]-phthalide 

Relevant articles and documents

Trifluoromethyl group as a pharmacophore: Effect of replacing a CF 3 group on binding and agonist activity of a glucocorticoid receptor ligand

Compound 1, a potent glucocorticoid receptor ligand, contains a quaternary carbon bearing trifluoromethyl and hydroxyl groups. This paper describes the effect of replacing the trifluoromethyl group on binding and agonist activity of the GR ligand 1. The r