934418-72-1Relevant academic research and scientific papers
Design and synthesis of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0 2,6]undec-4-yl]-2-trifluoromethyl-benzonitriles as androgen receptor antagonists
Xiao, Hai-Yun,Balog, Aaron,Attar, Ricardo M.,Fairfax, David,Fleming, Linda B.,Holst, Christian L.,Martin, Gregory S.,Rossiter, Lana M.,Chen, Jing,Cvjic, Mary-Ellen,Dell-John, Janet,Geng, Jieping,Gottardis, Marco M.,Han, Wen-Ching,Nation, Andrew,Obermeier, Mary,Rizzo, Cheryl A.,Schweizer, Liang,Spires Jr., Thomas,Shan, Weifang,Gavai, Ashvinikumar,Salvati, Mark E.,Vite, Gregory
scheme or table, p. 4491 - 4495 (2010/10/02)
A novel series of 4-[3,5-dioxo-11-oxa-4,9-diazatricyclo[5.3.1.0 2,6]undec-4-yl]-2-trifluoromethyl-benzonitriles has been synthesized. The ability of these compounds to act as antagonists of the androgen receptor was investigated and several wer
Tricycloundecane compounds useful as modulators of nuclear hormone receptor function
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Page/Page column 24, (2008/06/13)
Tricycloundecanes compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds are disclosed.
