93444-69-0

Upstream product

• 93444-71-4 2-bromo-7-(2-hydroxy-4-methylanilino)tropone 

Downstream Products

• 120624-30-8 2-{[1-(8-Methyl-10H-phenoxazin-1-yl)-meth-(E)-ylidene]-amino}-phenol 
• 120624-26-2 2-(2-Methyl-5-oxa-11-aza-cyclohepta[b]naphthalen-10-ylamino)-phenol 
• 120624-21-7 4-Methyl-2-{[1-(8-methyl-10H-phenoxazin-1-yl)-meth-(E)-ylidene]-amino}-phenol 
• 120624-20-6 4-Methyl-2-(2-methyl-5-oxa-11-aza-cyclohepta[b]naphthalen-10-ylamino)-phenol 

Relevant academic research and scientific papers

Intermolecular Bromine Transfer of 2-Amino-7-bromotropone Derivatives Catalyzed by Strong Acid

Upon heating acetic acid containing a trace of concd sulfuric acid at 120 deg C under nitrogen, 2-bromo-7-(2-hydroxyanilino)tropone (1a) gave 6-bromocycloheptabenzoxazine (2a) as the main product and cycloheptabenzoxazine, its 6,8-dibromo derivative and trace amounts of other mono, di-, and tribromo compounds.This reaction became much more complex in the presence of oxygen.A similar bromine transfer was observed for 2-bromo-7-(dimethylamino)-, 7-(2-hydroxy-5-methylanilino)-, and 7-(2-methoxyanilino)tropone although the cite of the intermolecular bromine transfer depended upon the structures of the substrates and the reaction conditions.In contrast, 2a and 2-amino-5-bromotropone derivatives were completely stable towards the strong acid.Possible reaction pathways for this bromine transfer reaction are discussed.