93454-41-2Relevant academic research and scientific papers
Total Synthesis of a Mitosene
Rebek, Julius,Shaber, Steven H.,Shue, Youe-Kong,Gehret, Jean-Claude,Zimmerman, Stephen
, p. 5164 - 5174 (2007/10/02)
The total synthesis of a mitosene (a chemical degradation product of mitomycin C) is described.The synthesis begins with hydroxyproline and uses a Huisgen pyrrole synthesis to form a pyrrolizidine system.The carbocyclic ring is made through Dieckmann cycl
