934562-65-9

Basic information

• Product Name: (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol
• Synonyms: (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol
• CAS NO: 934562-65-9
• Molecular Weight: 352.044
• Mol File: 934562-65-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol(934562-65-9)
• EPA Substance Registry System: (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl alcohol(934562-65-9)

Safety Data

• Hazardous Substances Data: 934562-65-9(Hazardous Substances Data)

Upstream product

• 33719-74-3 3,5-dichloroanisole 
• 89-75-8 2,4-dichlorobenzoyl chloride 
• 954143-59-0 (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl nonanoate 
• 954143-62-5 (2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl 2,2,2-trifluoroacetate 
• 934562-64-8 (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methanone 

Downstream Products

• 954143-59-0 (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl nonanoate 
• 934562-89-7 C₂₁H₁₃Cl₅O₃ 
• 954143-60-3 (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl)methyl (2R)-2-(tert-butoxycarbonylamino)propanoate 
• 954143-62-5 (2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl 2,2,2-trifluoroacetate 
• 1205121-89-6 (2,6-dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidate 
• 1007599-81-6 C₁₅H₁₂Cl₄N₂O₃ 
• 1007599-79-2 C₂₀H₂₀Cl₄N₂O₅ 
• 1134031-84-7 C₂₈H₂₆Cl₄O₁₂ 
• 1134031-94-9 C₂₈H₂₆Cl₄O₁₂ 

Relevant articles and documents

A new protecting group and linker for uridine ureido nitrogen

(2,6-Dichloro-4-methoxyphenyl)(2,4,6-trichlorophenyl) methoxymethyl chloride [1, monomethoxydiph-enylmethoxylmethyl chloroide (MDPM-Cl)] shows a significant relative stability and 1 reacts with uridine ureido nitrogen in the presence of DBU to form the corresponding protected uridine 8 in 95% yield. The MDPM-protected uridines are stable to a wide variety of conditions utilized for the synthesis of analogs of capuramycin and muraymycins. Significantly, the MDPM protecting group can conveniently be deprotected by using 30% TFA in CH 2Cl2. In addition, polymer-bound MDPM-Cl 23 is useful for immobilization of uridine derivatives.

(2,6-Dichloro-4-alkoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidates: Protection of alcohols and carboxylic acids in solution or on polymer support

(2,6-Dichloro-4-methoxyphenyl)-(2,4-dichlorophenyl)-methyl trichloroacetimidate can be efficiently activated by TMSOTf (10-100 mol%) to react with alcohols and carboxylic acids. Under these conditions a wide variety of alcohols can be transformed into the corresponding ethers in excellent yields with a slight excess of the trichloroacetimidate. The resulting ethers are not susceptible to typical deprotection conditions for benzyl and 4-methoxybenzyl ether groups, however, they can be conveniently deprotected by treatment with 30-50% trifluoroacetic acid in dichloromethane. Polymer-bound (2,6-dichloro-4-alkoxyphenyl)-(2,4-dichlorophenyl)methyl trichloroacetimidate is useful for immobilization of alcohols and carboxylic acids.

Polymer-supported (2,6-dichloro-4-alkoxyphenyl)(2,4-dichlorophenyl) methanol: A new linker for solid-phase organic synthesis

(Chemical Equation Presented) An acid and base stable hydroxytetrachlorodiphenylmethyl (HTPM) linker is developed for polymer-supported organic synthesis. The linkers reported here are utilized for loading carboxylic acids, amines, alcohols, and phenols, and are stable to Bronsted and Lewis acids, Bronsted bases, and a wide variety of nucleophiles. However, the HTPM linkers can conveniently be cleaved by the solvolytic displacement reactions with 20% TFA.