934619-55-3

Upstream product

• 771578-92-8 (2S,3S)-2-(N-tert-butoxycarbonyl-N-methylamino)-5-(tert-butyldimethylsiloxy)-3-methylpentanoic acid benzyl ester 
• 474550-00-0 2-[1-(S)-t-butoxycarbonylaminoethyl]-4-(R)-methyl-4,5-dihydrothiazole-4-carboxylic acid methyl ester 
• 878632-95-2 (R)-2-[(S)-1-(9H-Fluoren-9-ylmethoxycarbonylamino)-ethyl]-4-methyl-4,5-dihydro-thiazole-4-carboxylic acid methyl ester 
• 878632-97-4 (2S,3S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-methyl-2-methylamino-pentanoic acid benzyl ester 
• 878632-96-3 (R)-2-((S)-1-tert-Butoxycarbonylamino-ethyl)-4-methyl-4,5-dihydro-thiazole-4-carboxylic acid 
• 934619-58-6 2-{[2-(1-tert-butoxycarbonylamino-ethyl)-4-methyl-4,5-dihydro-thiazole-4-carbonyl]-methyl-amino}-5-(tert-butyl-dimethyl-silanyloxy)-3-methyl-pentanoic acid benzyl ester 

Downstream Products

• 934619-59-7 5-(tert-butyl-dimethyl-silanyloxy)-2-{[2-(1-{3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionyloxy]-7-methoxy-2,2,4-trimethyl-decanoylamino}-ethyl)-4-methyl-4,5-dihydro-thiazole-4-carbonyl]-methyl-amino}-3-methyl-pentanoic acid benzyl ester 

Relevant academic research and scientific papers

Total synthesis of halipeptin A, a potent anti-inflammatory cyclodepsipeptide from a marine sponge

Total synthesis of halipeptin A, a potent anti-inflammatory cyclodepsipeptide, was achieved through proline-catalyzed asymmetric α-oxidation, diastereoselective aldol reaction, silver cyanide-mediated esterification, and macrolactamization.