934698-40-5

Upstream product

• 120343-66-0 (R)-1-(1-phenylethyl)tetrahydro-4(1H)-pyridinone 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 1213240-56-2 (3R,4R,5S)-4-(2-chlorophenyl)-2,3-diphenyl-7-[(R)-1-phenylethyl]-1-oxa-2,7-diazaspiro[4.5]decan-10-one 
• 1213240-45-9 (3S,4S,5R)-4-(2-chlorophenyl)-2,3-diphenyl-7-[(R)-1-phenylethyl]-1-oxa-2,7-diazaspiro[4.5]decan-10-one 
• 1213240-57-3 (3R,4R,5S)-4-(2-chlorophenyl)-3-(4-methylphenyl)-2-phenyl-7-[(R)-1-phenylethyl]-1-oxa-2,7-diazaspiro[4.5]decan-10-one 
• 1213240-46-0 (3S,4S,5R)-4-(2-chlorophenyl)-3-(4-methylphenyl)-2-phenyl-7-[(R)-1-phenylethyl]-1-oxa-2,7-diazaspiro[4.5]decan-10-one 

Relevant academic research and scientific papers

1,3-Dipolar cycloaddition of nitrile oxides to (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones: synthesis of enantiomerically pure spiro heterocycles

The 1,3-dipolar cycloaddition of (R)-1-(1-phenylethyl)-3-[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones to nitrile oxides proceeds chemo-, regio-, and stereoselectively affording moderate yields of enantiomerically pure spiro heterocycles comprising pi