934752-09-7Relevant academic research and scientific papers
Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones
van Oeveren, Arjan,Pio, Barbara A.,Tegley, Christopher M.,Higuchi, Robert I.,Wu, Min,Jones, Todd K.,Marschke, Keith B.,Negro-Vilar, Andres,Zhi, Lin
, p. 1523 - 1526 (2007/10/03)
A series of alkylamino-2-quinolinone compounds (3) was discovered as androgen receptor modulators based on an early linear tricyclic quinoline pharmacophore (1). The series demonstrated selective high binding affinity to androgen receptor and potent recep
