934828-17-8

Basic information

• Product Name: benzyl 4-{4-[({2-[(tert-butoxycarbonyl)amino]phenyl}amino)carbonyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate
• Synonyms: benzyl 4-{4-[({2-[(tert-butoxycarbonyl)amino]phenyl}amino)carbonyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate
• CAS NO: 934828-17-8
• Molecular Weight: 527.62
• Mol File: 934828-17-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl 4-{4-[({2-[(tert-butoxycarbonyl)amino]phenyl}amino)carbonyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 4-{4-[({2-[(tert-butoxycarbonyl)amino]phenyl}amino)carbonyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate(934828-17-8)
• EPA Substance Registry System: benzyl 4-{4-[({2-[(tert-butoxycarbonyl)amino]phenyl}amino)carbonyl]phenyl}-3,6-dihydropyridine-1(2H)-carboxylate(934828-17-8)

Safety Data

• Hazardous Substances Data: 934828-17-8(Hazardous Substances Data)

Upstream product

• 617703-01-2 N-(2-(tert-butoxycarbonylamino)phenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide 
• 286961-24-8 benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate 

Downstream Products

• 934828-07-6 tert-butyl 2-[(4-piperidin-4-ylbenzoyl)amino]phenylcarbamate 

Relevant articles and documents

Design and campaign synthesis of piperidine- and thiazole-based histone deacetylase inhibitors

A lead benzamide, 3, was identified as a potent and low molecular weight histone deacetylase (HDAC) inhibitor. Optimization led to 16d, demonstrating an excellent balance of efficacy and non-efficacy properties, along with very desirable in vivo DMPK. The