934844-86-7Relevant academic research and scientific papers
Design, synthesis, and structure - Activity relationship of N-arylnaphthylamine derivatives as amyloid aggregation inhibitors
Di Santo, Roberto,Costi, Roberta,Cuzzucoli Crucitti, Giuliana,Pescatori, Luca,Rosi, Federica,Scipione, Luigi,Celona, Diana,Vertechy, Mario,Ghirardi, Orlando,Piovesan, Paola,Marzi, Mauro,Giorgi, Fabrizio,Minetti, Patrizia,Caccia, Silvio,Guiso, Giovanna
, p. 8538 - 8548,11 (2020/09/15)
Dyes like CR are able to inhibit the aggregation of Aβ fibrils. Thus, a screening of a series of dyes including ABBB (1) was performed. Its main component 2 tested in an in vitro assay (i.e., ThT assay) showed good potency at inhibiting fibrils associatio
NAPHTHYL DERIVATIVES INHIBITORS OF THE BETA-AMYLOID AGGREGATION
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Page/Page column 23-25, (2008/06/13)
Compounds useful in the treatment of disorders characterised by deposits of amyloid aggregates are herein described together with pharmaceutical compounds containing the same. In particular the compounds of the present invention are those having the Formula (I) as reported below. where the radicals have the meaning indicated in the description.
