934992-79-7

Upstream product

• 934992-78-6 2-nitro-5-(1H-pyrazol-1-yl)aniline 
• 1635-61-6 5-chloro-2-nitroaniline 

Downstream Products

• 1445863-58-0 4-[5-chloro-2-(1H-tetrazol-1-yl)phenyl]-1-{2-phenyl-1-[5-(1H-pyrazol-1-yl)-1H-benzimidazol-2-yl]ethyl}-2(1H)-pyridinone 
• 1445865-93-9 N-[2-amino-4-(1H-pyrazol-1-yl)phenyl]-2-{4-[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-2-oxo-1,2-dihydropyridin-1-yl}-3-phenylpropanamide 

Relevant academic research and scientific papers

PYRIDINONE AND PYRIMIDINONE DERIVATIVES AS FACTOR XIA INHIBITORS

The present invention provides compounds of the general formula (I), their salts and N- oxides, and solvates and prodrugs thereof (wherein the characters are as defined in the description). The compounds of the general formula (I) are inhibitors of Factor XIa, so that they are useful in the prevention of and/or therapy for thromboembolic diseases.

OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS

The present invention provides a novel class of oligoheteroaromatic assemblies with luminescence characteristics and composition based on integrated polyheterocyclic polyamide oligomers of multiple nitrogen-containing heteroaromatic of the general formula (I) This novel class of compounds of the present invention is capable of binding to targeted DNA sequence in the minor groove, and thus is useful for genomics applications. In particular, the compounds of the invention binds to the DNA at a binding stoichiometry of 2: 1 ternary complexation with very high affinity and sequence selectivity.