93501-34-9

Upstream product

• 71-43-2 benzene 
• 93500-95-9 2,3-Dibromo-3-(4-chloro-phenyl)-N-phenyl-propionamide 
• 93501-21-4 2-Bromo-3-(4-chloro-phenyl)-3,N-diphenyl-propionamide 

Downstream Products

• 93501-08-7 4-(4-chlorophenyl)-2-quinolinone 
• 93501-07-6 4-(4-chlorophenyl)-4-phenyl-3,4-dihydroquinolin-2(1H)-one 

Relevant academic research and scientific papers

Direct transformation of arylpropynes to acrylamides via a three-step tandem reaction

A novel and metal-free acrylamides formation between arylpropynes and hydroxylamine hydrochloride through sp3 C-H and C-C bond cleavage has been achieved with DDQ as an oxidant. The mechanistic study shows that the acrylamides are formed through a three-step tandem sequence, including cross-dehydrogenative-coupling (CDC) reaction, aza-Meyer-Schuster rearrangement and Beckmann rearrangement. This journal is The Royal Society of Chemistry 2014.

A New Route for the Synthesis of Coumarins, Thiacoumarins and Carbostyrils

3-Arylcarbostyrils, coumarins and thiacoumarins (3) have been prepared from the respective β-aryl-α-bromodihydrocinnamoyl derivatives (2) by treatment with AlCl3.The β,β-diarylacrylic acid derivatives (4) and (9), obtained from 2, on reaction with AlCl3 afford 4-arylcarbostyrils (5) 6-methyl-4-phenylthiacoumarin (10) respectively.However the oxygen analogs (11) give 3,3-diphenyl-1-indanone (12)