93503-52-7

Downstream Products

• 93503-62-9 4-(1-ethyl-2-phenyl-1H-indol-3-yl)-3-cyclohexene-1,1-dicarboxylic acid 
• 93503-63-0 4-(1-Ethyl-2-phenyl-1H-indol-3-yl)-cyclohex-3-ene-1,1-dicarboxylic acid dimethyl ester 
• 93503-71-0 dimethyl-4-(1-methyl-2-phenyl-1H-indol-3-yl)-1,1-cyclohexanedicarboxylate 
• 93503-55-0 4-(1-Methyl-2-phenyl-1H-indol-3-yl)-cyclohex-3-ene-1,1-dicarboxylic acid dimethyl ester 
• 93503-70-9 cis-4-(1-methyl-2-phenyl-1H-indol-3-yl)-1,1-cyclohexanedicarboxylic acid monomethyl ester 
• 93503-53-8 dimethyl 4-(2-phenyl-1H-indol-3-yl)-3-cyclohexene-1,1-dicarboxylate 
• 93503-64-1 4-(2-phenyl-1H-indol-3-yl)cyclohexane-1,1-dicarboxylic acid 

Relevant academic research and scientific papers

2-Phenylindole derivatives, their use as complement inhibitors

4-(1-R'-2-phenyl-1H-indol-3-yl)-3-cyclohexene-1-carboxylic acids, 4-(1'R'-2-phenyl-1H-indol-3-yl)cyclohexane-1-carboxylic acids, 4-(1-R'-2-phenyl-1H-indol-3-yl)benzoic acids, the corresponding cyclohexene- and cyclohexane-1,1-dicarboxylic acids, and lower-alkyl esters thereof, wherein R' is hydrogen or lower-alkyl, are prepared by reacting a 1-R'-2-phenyl-1H-indole with a cyclohexanone-4-carboxylic acid or -4,4-dicarboxylic acid, followed as desired by a hydrogenation or aromatization process. The compounds which are free carboxylic acids or salts thereof are useful as complement inhibitors. The corresponding esters are useful as intermediates.