93525-18-9Relevant articles and documents
Utility of microbes in organic synthesis: Selective transformations of acyclic isoprenoids by Aspergillus niger
Madyastha, K M,Gururaja, T L
, p. 609 - 614 (2007/10/02)
Bioconversion of acyclic isoprenoids using a strain of Aspergillus niger results in hydroxylated metabolites with regio- and stereoselectivity.The organism carries out oxidation of the terminal allylic methyl group and the remote double bond in all the compounds tested (I-VII).However, these two activities seem to have preferential structural requirements.When an acyclic isoprenoid with a ketone functionality such as geranylacetone is used as the substrate, the organism also carries out the asymmetric reduction of the keto group.All the metabolites formed have beenpurified and characterized by conventional spectroscopic methods and quantification has been made by gas chromatographic analyses.