935265-03-5

Upstream product

• 172277-78-0 (5R,6R)-6-(hydroxymethyl)-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one 
• 172172-72-4 (5R,6R)-6-[(1,1-dimethylethyl)dimethylsilyloxymethyl]-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-one 
• 6485-40-1 (R)-Carvone 
• 935265-01-3 (1S,5R,6R)-6-[(1,1-dimethylethyl)dimethylsilyloxymethyl]-2-methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol 
• 935264-92-9 (1S,2S,3R,4R,6R)-3-[(1,1-dimethylethyl)dimethylsilyloxymethyl]-1-methyl-4-(1-methylethenyl)-7-oxabicyclo[4.1.0]heptan-2-ol 
• 2746-25-0 p-Methoxybenzyl bromide 

Downstream Products

• 935264-96-3 [(1R,2S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-2-(4-methoxybenzyloxy)-3-methylcyclohex-3-en-1-yl]carbaldehyde 
• 935265-09-1 (1R,5S,6S)-6-(1,1-dimethylethyl)dimethylsilyloxymethyl-5-(4-methoxybenzyloxy)-4-methylcyclohex-3-en-1-ol 
• 935265-12-6 [(1R,2S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-2-(4-methoxybenzyloxy)-3-methylcyclohex-3-en-1-yl]methanol 
• 935265-07-9 (1R,5S,6S)-6-(1,1-dimethylethyl)dimethylsilyloxymethyl-5-(4-methoxybenzyloxy)-4-methylcyclohex-3-en-1-yl acetate 
• 1026950-71-9 2-[6-(tert-butyl-dimethyl-silanyloxy)-2-(4-methoxy-benzyloxy)-3-methyl-cyclohex-3-enyl]-2-methoxy-ethylamine 
• 935265-05-7 1-{(1R,3R,4R,5S,6R)-4-(1,1-dimethylethyl)dimethylsilyloxymethyl-5-(4-methoxybenzyloxy)-6-methyl-7-oxabicyclo[4.1.0]heptan-3-yl}ethan-1-one 
• 935264-89-4 {(1R,5S,6S)-6-[(1S)-methoxy-2-nitroethyl]-5-(4-methoxybenzyloxy)-4-methylcyclohex-3-en-1-yloxy}(1,1-dimethylethyl)dimethylsilane 
• 935264-94-1 (1R,3R,4S,5S,6R)-4-[(1,1-dimethylethyl)dimethylsilyloxymethyl]-5-(4-methoxybenzyloxy)-6-methyl-7-oxabicyclo[4.1.0]heptan-3-yl acetate 
• 935264-98-5 (1S)-1-[(1R,2S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-2-(4-methoxybenzyloxy)-3-methylcyclohex-3-en-1-yl]-2-nitroethan-1-ol 
• 935265-10-4 [(1R,2S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-2-(4-methoxybenzyloxy)-3-methylcyclohex-3-en-1-yl]methoxy(1,1-dimethylethyl)dimethylsilane 
• 935264-84-9 (4E,7S)-N-{(2S)-[(1S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-3-methyl-2-oxocyclohex-3-en-1-yl]-2-methoxyethyl}-7-methoxydodec-4-enamide 
• 935264-83-8 (4E,7S)-N-{(2S)-[(1S,2S,6R)-6-(1,1-dimethylethyl)dimethylsilyloxy-2-(4-methoxybenzyloxy)-3-methylcyclohex-3-en-1-yl]-2-methoxyethyl}-7-methoxydodec-4-enamide 

Relevant academic research and scientific papers

Total synthesis and correct absolute configuration of malyngamide U

The enantioselective synthesis of the previously proposed structure of malyngamide U (1) was accomplished in 18 steps from (S)-(+)-carvone. The key steps involved a hydroxymethylation of (S)-(+)-carvone and an asymmetric Henry reaction of aldehyde (+)-5,