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Usage

Uses

Used in Organic Synthesis:
t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate is used as a synthetic intermediate for the formation of carbon-carbon and carbon-heteroatom bonds, leveraging its boron-containing moiety to facilitate coupling reactions in organic synthesis.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate is used as a building block for the development of novel drugs, capitalizing on its unique structure to create molecules with specific biological activities.
Used in Agrochemical Industry:
t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate is utilized as a key component in the synthesis of agrochemicals, such as pesticides and herbicides, due to its potential to form stable and effective compounds for crop protection.
Used in Materials Science:
In materials science, t-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1-carboxylate is employed in the development of new materials with tailored properties, such as polymers and composites, by incorporating its structural features to enhance performance characteristics.

InChI:InChI=1S/C15H24BNO4/c1-13(2,3)19-12(18)17-9-8-11(10-17)16-20-14(4,5)15(6,7)21-16/h8-10H,1-7H3

Upstream product

• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 475561-75-2 3-bromopyrrole-l-carboxylic acid tert-butyl ester 
• 5176-27-2 N-tert-butyloxycarbonyl-pyrrole 
• 73183-34-3 bis(pinacol)diborane 

Relevant academic research and scientific papers

RORC2 INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions.

Boc groups as protectors and directors for ir-catalyzed C-H borylation of heterocycles

(Chemical Equation Presented) Ir-catalyzed C-H borylation is found to be compatible with Boc protecting groups. Thus, pyrroles, indoles, and azaindoles can be selectively functionalized at C-H positions β to N. The Boc group can be removed on thermolysis

Microwave-accelerated iridium-catalyzed borylation of aromatic C-H bonds

Image Persented Microwave heating accelerates the Ir-catalyzed C-H borylation of aromatic substrates when compared with reactions carried out at the same temperature under standard heating conditions. Application to a one-pot single solvent process for ta

Synthesis of rhazinicine by a metal-catalyzed C-H bond functionalization strategy

(Chemical Equation Presented) Iterative and regioselective metal-catalyzed C-H bondfunctionalization has been utilizedto develop a strategy for the first total synthesis of the pyrrole alkaloid rhazinicine (see scheme).

Highly efficient monophosphine-based catalyst for the palladium-catalyzed Suzuki-Miyaura reaction of heteroaryl halides and heteroaryl boronic acids and esters

A highly active and efficient catalyst system derived from a palladium precatalyst and monophosphine ligands 1 or 2 for the Suzuki-Miyaura cross-coupling reaction of heteroaryl boronic acids and esters has been developed. This method allows for the preparation of a wide variety of heterobiaryls in good to excellent yields and displays a high level of activity for the coupling of heteroaryl chlorides as well as hindered aryl and heteroaryl halides. Specific factors that govern the efficacy of the transformation for certain heterocyclic motifs were also investigated.