935458-01-8Relevant academic research and scientific papers
Site-specific incorporation of glycosylated serine and tyrosine derivatives into proteins
Fahmi, Nour Eddine,Dedkova, Larisa,Wang, Bixun,Golovine, Serguei,Hecht, Sidney M.
, p. 3586 - 3597 (2007)
Glycosylation of proteins can have a dramatic effect on their physical, chemical, and biological properties. Analogues of dihydrofolate reductase and firefly luciferase containing glycosylated amino acids at single, predetermined sites have been elaborate
Facile synthesis of glycosylated Fmoc amino acid building blocks assisted by microwave irradiation
Yao, Nianhuan,Fung, Gabriel,Malekan, Hamed,Ye, Long,Kurth, Mark J.,Lam, Kit S.
experimental part, p. 2277 - 2281 (2010/11/19)
The synthesis of glycosylated Fmoc amino acids by reaction of mono- and disaccharide peracetates with Fmoc amino acids having free carboxyl groups was rapidly promoted by Lewis acids (SnCl4, BF3·Et 2O) under microwave irradiation. The products are useful building blocks for the synthesis of glycopeptides.
