935547-66-3Relevant academic research and scientific papers
Straightforward access to simplified sphingosine-1-phosphate analogues
Grijalvo, Santiago,Llebaria, Amadeu,Delgado, Antonio
, p. 2737 - 2751 (2008/02/12)
A straightforward approach for the synthesis of a new series of amino phosphates structurally related to sphingosine-1-phosphate is described. The commercial availability of the required starting building blocks, the reduced number of steps, and the ease
Design, synthesis and activity as acid ceramidase inhibitors of 2-oxooctanoyl and N-oleoylethanolamine analogues
Grijalvo, Santiago,Bedia, Carmen,Triola, Gemma,Casas, Josefina,Llebaria, Amadeu,Teixido, Jordi,Rabal, Obdulia,Levade, Thierry,Delgado, Antonio,Fabrias, Gemma
, p. 69 - 84 (2007/10/03)
The synthesis of novel N-acylethanolamines and their use as inhibitors of the aCDase is reported here. The compounds are either 2-oxooctanamides or oleamides of sphingosine analogs featuring a 3-hydroxy-4,5-hexadecenyl tail replaced by ether or thioether
