935551-91-0

Upstream product

• 935551-89-6 N-((4-fluorophenyl)(tosyl)methyl)benzamide 
• 219729-65-4 2-(propylthio)pyrimidine-4-carboxaldehyde 

Downstream Products

• 935551-93-2 tert-butyl 2-((4R,6R)-6-(2-(4-(4-fluorophenyl)-2-phenyl-5-(2-(propylthio)pyrimidin-4-yl)-1H-imidazol-1-yl)ethyl)-2-phenyl-1,3,2-dioxaborinan-4-yl)acetate 

Relevant academic research and scientific papers

COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE

The present invention provides compositions of matter, kits and methods for their use in the treatment of MAP kinase-related conditions and/or HMG-CoA reductase-related conditions. In particular, the invention provides compositions for treating inflammatory and/or cardiovascular conditions in an animal subject by inhibiting ρ38αMAP kinase and/or HMG-CoA reductase, as well as providing formulations and modes of administering such compositions. The invention further provides methods for the rational design of inhibitors of MAP kinase, HMG-CoA reductase, or both for use in the practice of the present invention.