935559-75-4Relevant academic research and scientific papers
Competitive cationic pathways and the asymmetric synthesis of aryl-substituted cyclopropanes
Melancon, Bruce J.,Perl, Nicholas R.,Taylor, Richard E.
, p. 1425 - 1428 (2007)
Equation presented 1,2-Disubstituted cyclopropanes were synthesized in a nonracemic fashion via activation of the corresponding homoallylic alcohols in excellent yields. A series of substituted phenyl rings showed higher enantiospecificity for the cyclization as the electron-withdrawing ability of the group increased. The results offer strong support for the existence of competing cation mechanisms.
Chiral phosphoric acid catalyzed enantioselective allylation of aldehydes with allyltrichlorosilane
Cheng, Ke,Fan, Tiantian,Sun, Jian
experimental part, p. 1669 - 1671 (2012/01/07)
Easily accessible chiral phosphoric acid 1b has been applied as efficient organocatalyst for the asymmetric allylation of aldehydes with allyltrichlorosilane. In the presence of 20 mol% of 1b, the allylation of a broad range of aldehydes proceeded smoothl
Asymmetrie allylation of aldehydes catalyzed by simple dual small organic molecules: L-proline and L-prolinol
Chen, Guo-Hong,Liu, Ling-Yan,Wei, Xiao-Ning,Chang, Wei-Xing,Li, Jing
scheme or table, p. 1013 - 1015 (2011/01/06)
A novel and simple methodology for the asymmetric allylation of aldehydes was reported. Double small organic molecules such as L-proline and L-prolinol were first employed for providing a chiral environment so as to afford chiral homoallylic alcohols in high yields and moderate enantioselectivities in our protocol.
