935681-52-0Relevant articles and documents
Bis-cycloSal-d4T-monophosphates: Drugs that deliver two molecules of bioactive nucleotides
Ducho, Christian,G?rbig, Ulf,Jessel, S?nke,Gisch, Nicolas,Balzarini, Jan,Meier, Chris
, p. 1335 - 1346 (2008/02/02)
Bis-cycloSal-d4T-monophosphates have been synthesized as potentially anti-HIV active "dimeric" prodrugs of 2′,3′-dideoxy- 2′,3′-didehydrothymidine monophosphate (d4TMP). These pronucleotides display a mask-drug ratio of 1:2, a novelty in the field of pron