935684-39-2Relevant academic research and scientific papers
Quinol derivatives as potential trypanocidal agents
Capes, Amy,Patterson, Stephen,Wyllie, Susan,Hallyburton, Irene,Collie, Iain T.,McCarroll, Andrew J.,Stevens, Malcolm F.G.,Frearson, Julie A.,Wyatt, Paul G.,Fairlamb, Alan H.,Gilbert, Ian H.
, p. 1607 - 1615 (2012)
Quinols have been developed as a class of potential anti-cancer compounds. They are thought to act as double Michael acceptors, forming two covalent bonds to their target protein(s). Quinols have also been shown to have activity against the parasite Trypa
Quinols as novel therapeutic agents. 7. Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions
McCarroll, Andrew J.,Bradshaw, Tracey D.,Westwell, Andrew D.,Matthews, Charles S.,Stevens, Malcolm F. G.
, p. 1707 - 1710 (2008/02/02)
Interaction of 2-iodoaniline or 5-fluoro-2-iodoaniline with a range of arylsulfonyl chlorides affords sulfonamides that undergo Sonogashira couplings under thermal or microwave conditions with the alkyne 4-ethynyl-4- hydroxycyclohexa-2,5-dien-1-one follow
