935692-29-8Relevant academic research and scientific papers
Design, synthesis and evaluation of MCH receptor 1 antagonists - Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition
Roth, Gerald J.,Heckel, Armin,Kley, J?rg T.,Lehmann, Thorsten,Müller, Stephan G.,Oost, Thorsten,Rudolf, Klaus,Arndt, Kirsten,Budzinski, Ralph,Lenter, Martin,Lotz, Ralf R.H.,Schindler, Marcus,Thomas, Leo,Stenkamp, Dirk
, p. 3270 - 3274 (2015)
Abstract Despite recent success there remains a high therapeutic need for the development of drugs targeting diseases associated with the metabolic syndrome. As part of our search for safe and effective MCH-R1 antagonists for the treatment of obesity, a s
