93585-23-0Relevant academic research and scientific papers
Cyclization of 4,5-diamino pyrazole derivatives and their antibacterial activities
Rizk, Hala F.,Ei-Badawi, Mahmoud A.,Ibrahim, Seham A.,Ei-Borai, Mohamed A.
, p. 1451 - 1459 (2011/10/30)
A convenient synthesis of intermediate 4,5-diamino-3-aryl-1-phenylpyrazoles 4a-4c was reported. The different cyclization reactions were carried out with chalcone, 2-mercaptoacetic acid and p-anisialdehyde, ethyl chloroformate, glyoxal and thiourea to afford different N and S containing heterocycles. The reaction conditions were compared by conventional heating and microwave irradiation. The structures of the cyclization products were determined by analytical and spectroscopic data. All the synthesized compounds were screened for antibacterial activities in vitro. Copyright
Synthesis of Several New Pyrazolotriazoles, Imidazo-pyrazoles, and Pyrazolopyrazines. Reaction of Nitrilimines with Amino- and Oxo-substituted Azoles. II
Elgemeie, G. E. H.,Elfahham, H. A.,Ghozlan, S. A. S.,Elnagdi, M. H.
, p. 1650 - 1652 (2007/10/02)
The reactivity of amino and hydroxy azoles toward nitrilimines and hydrazonoyl halides was investigated.Several novel rotes for synthesis of derivatives of known heterocyclic systems are reported.
