935863-96-0

Upstream product

• 935982-61-9 6-fluoro-8-(4-methyl-piperazin-1-yl)-chroman-2-carboxylic acid 

Downstream Products

• 935863-97-1 (rac)-6-fluoro-8-(4-methyl-piperazin-1-yl)-N-(4-(morpholin-4-yl)phenyl)chroman-2-carboxamide 

Relevant academic research and scientific papers

CHROMAN COMPOUNDS AS 5 HT1B ANTAGONISTS

Compounds according to Formula (I) wherein X and R are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.

CHROMAN COMPOUNDS AS 5-HT1B ANTAGONISTS

Chroman derivatives according to formula (I), wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same. The compounds are 5-HT1B antagonists and are useful in the treatment of mood and anxiety disorders .as well as cognitive disorders.

CHROMAN COMPOUNDS AS 5 -HTlB ANTAGONISTS

Chroman derivatives according to Formula (I) below: wherein R1, R2, R3 ,and R4 are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical .compositions containing a