936075-08-0Relevant articles and documents
Phenyliodonium diacetate mediated arylation of benzothiazoles with substituted styrenes
Kamal, Ahmed,Reddy, N.V. Subba,Prasad
, p. 3972 - 3975 (2014)
A metal-free synthesis of 2-arylbenzothiazoles was achieved using phenyliodonium diacetate (PIDA) from benzothiazoles and styrenes or β-nitrostyrenes. This transformation tolerates various functional groups such as methoxy, hydroxy, fluoro, chloro, and nitro groups.
T -BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes
Liu, Xia,Zhao, Xin,Liang, Fushun,Ren, Baoyi
supporting information, p. 886 - 890 (2018/02/19)
An efficient halogenation of electron-deficient (hetero)arenes is described. The reaction utilizes common t-BuONa as a catalyst (for iodination) or a promoter (for bromination and chlorination), and perfluorobutyl iodide, CBr4 or CCl4 as the readily-available halogenating agents, respectively. The protocol features broad scope, high efficiency, mild conditions and gram scalability. An ionic pathway involving halogen bond formation and halophilic attack is proposed. The utility of the resulting iodinated heteroarenes is demonstrated in visible light-mediated Caryl-Caryl cross-coupling reaction.
Iron-catalyzed cyclization of aminothiols: An easy access to benzothiazoles and evaluation of their antimicrobial and anti-biofilm activities
Vinayak, Bolla,Reddy, Marri Anil,Chiranjeevi, Barreddi,Chandrashekharam, Malapaka,Poornachandra,Ganesh Kumar
, p. 461 - 470 (2017/01/18)
Iron-catalyzed cyclization of aminothiol with various aromatic and heteroaromatic aldehydes produces a variety of benzothiazoles in moderate to excellent yield. Compound 3o with one carbazole functional moiety bridged between two benzothiazole scaffolds i
