936107-38-9Relevant articles and documents
Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety
Yang, Shu-Wei,Ho, Ginny,Tulshian, Deen,Greenlee, William J.,Tan, Zheng,Zhang, Hongtao,Smith-Torhan, April,Fawzi, Ahmad,Anthes, John,Lu, Sherry,Varty, Geoffrey,Fernandez, Xiomara,McLeod, Robbie L.,Hey, John
scheme or table, p. 2482 - 2486 (2009/12/25)
A series of nortropane analogs based on previously reported compound 1 have been synthesized and shown to bind to the nociceptin receptor with high affinity. The synthesis and structure-activity relationships around the C-3 nortropane substitution are des