93621-38-6 Usage
General Description
1-METHYL-4-ETHOXYCARBONYL PYRAZOLE-5-SULFONYL CHLORIDE is a chemical compound with the molecular formula C10H12ClN3O4S and a molecular weight of 311.74 g/mol. It is a sulfonyl chloride derivative of pyrazole, containing a methyl and ethoxycarbonyl substituent. 1-METHYL-4-ETHOXYCARBONYL PYRAZOLE-5-SULFONYL CHLORIDE is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its reactivity and ability to facilitate the formation of various types of chemical bonds. 1-METHYL-4-ETHOXYCARBONYL PYRAZOLE-5-SULFONYL CHLORIDE has been studied for its potential applications in the development of new drugs and has demonstrated promising biological activities in laboratory experiments. However, its chemical properties and potential hazards should be handled with caution in a controlled laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 93621-38-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,6,2 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 93621-38:
(7*9)+(6*3)+(5*6)+(4*2)+(3*1)+(2*3)+(1*8)=136
136 % 10 = 6
So 93621-38-6 is a valid CAS Registry Number.
93621-38-6Relevant articles and documents
Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors
Zhang, Peilong,Dong, Jiaqiang,Zhong, Boyu,Zhang, Deyi,Yuan, Hongbin,Jin, Can,Xu, Xiangyuan,Li, Hailong,Zhou, Yong,Liang, Zhi,Ji, Minghua,Xu, Tao,Song, Guowei,Zhang, Ling,Chen, Gang,Meng, Xuejing,Sun, Desheng,Shih, Joe,Zhang, Ruihao,Hou, Guojun,Wang, Chengcheng,Jin, Ying,Yang, Qiong
, p. 1910 - 1918 (2016/04/09)
Anaplastic lymphoma kinase (ALK) is a highly attractive therapeutic target for the treatment of some non-small cell lung cancer patients. This Letter describes the further SAR exploration on the novel 3-sulfonylpyrazol-4-amino pyrimidine scaffold. This work identified a compound 53 with very good in vitro/in vivo efficacies, good DMPK properties together with better hERG tolerability and it is currently being profiled for the evaluation as a potential pre-clinical candidate.
Synthesis of some pyrazolo[4,3-e][1,2]- and thiazolo[4,5-e][1,2]thiazine 1,1-dioxide derivatives
Bellemin,Festal
, p. 1017 - 1021 (2007/10/02)
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