936216-53-4Relevant academic research and scientific papers
Palladium-catalyzed intramolecular arylation of N-benzyl-2-iodoimidazoles: A facile and rapid access to 5H-imidazo[2,1-α]isoindoles
De Figueiredo, Renata Marcia,Thoret, Sylviane,Huet, Caroline,Dubois, Joelle
, p. 529 - 540 (2007/12/29)
The first example of a Pd-catalyzed intramolecular arylation involving the C-2 position of an imidazole ring is presented. Application of this reaction led to the formation of 5H-imidazo[2,1-a]isoindole in one step from N-benzyl-2-iodoimidazole. Microwave irradiation enhanced the rate of reaction allowing the synthesis of various imidazo[2,1-a]isoindole analogues. Georg Thieme Verlag Stuttgart.
