936324-82-2Relevant academic research and scientific papers
A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists
Selvam, Chelliah,Oueslati, Nadia,Lemasson, Isabelle A.,Brabet, Isabelle,Rigault, Delphine,Courtiol, Tiphanie,Cesarini, Sara,Triballeau, Nicolas,Bertrand, Hugues-Olivier,Goudet, Cyril,Pin, Jean-Philippe,Acher, Francine C.
experimental part, p. 2797 - 2813 (2010/08/06)
(R)-PCEP (3-amino-3-carboxypropyl-2′-carboxyethyl phosphinic acid, 1), a new metabotropic glutamate receptor 4 (mGlu4R) agonist, was discovered in a previously reported virtual screening. The (S)-enantiomer and a series of derivatives were synthesized and
Hypophosphorous Acid Derivatives and their Therapeutical Applications
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Page/Page column 13-14, (2009/07/17)
Hypophosphorous acid derivatives having Formula (I) wherein .M is a [C(R3,R4)]n1-C(E,COOR1,N(H,Z)) group, or an optionally substituted Ar—CH(COOR1,N(H,Z)) group, or an a, β, or a β, g-cyclic amino acid; .R1 is H or R, R being an hydroxy or a ca
