936494-74-5

Basic information

• Product Name: 2-(4-BROMOPHENYL)-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL
• Synonyms: 2-(4-BROMOPHENYL)-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL
• CAS NO: 936494-74-5
• Molecular Formula: C₁₀H₁₃BrO₃
• Molecular Weight: 261.114
• Mol File: 936494-74-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(4-BROMOPHENYL)-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMOPHENYL)-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL(936494-74-5)
• EPA Substance Registry System: 2-(4-BROMOPHENYL)-2-(HYDROXYMETHYL)PROPANE-1,3-DIOL(936494-74-5)

Safety Data

• Hazardous Substances Data: 936494-74-5(Hazardous Substances Data)

Usage

Structure

A propylene backbone with a bromine-substituted phenyl group and a hydroxymethyl group attached

Usage

Commonly used in the synthesis of pharmaceuticals and chemical intermediates

Reactivity

The bromine in the compound can act as a leaving group in various organic reactions

Functionalization

The hydroxymethyl group provides a site for further functionalization

Potential applications

May have potential applications in medicinal chemistry and drug development due to its structural features

Handling precautions

Should be handled with caution due to its potential toxicity and reactivity.

Upstream product

• 4654-39-1 4-bromophenethanol 
• 50-00-0 formaldehyd 
• 27200-79-9 p-bromophenylacetaldehyde 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 1423702-61-7 C₁₂H₁₅BrO₄ 
• 14062-25-0 Ethyl 4-bromophenylacetate 

Downstream Products

• 1188264-15-4 [3-(4-bromophenyl)oxetan-3-yl]methanol 
• 1393585-20-0 3-(4-bromophenyl)oxetane-3-carboxylic acid 
• 1423702-65-1 methyl 3-(4-bromophenyl)oxetane-3-carboxylate 
• 1423702-68-4 methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)oxetane-3-carboxylate 
• 1423684-87-0 C₂₉H₂₆N₂O₆ 

Relevant articles and documents

Molybdenum tricarbonyl complex functionalised with a molecular triazatriangulene platform on Au(111): Surface spectroscopic characterisation

Transition metal complexes form the basis for small molecule activation and are relevant for electrocatalysis. To combine both approaches the attachment of homogeneous catalysts to metallic surfaces is of significant interest. Towards this goal a molybdenum tricarbonyl complex supported by a tripodal phosphine ligand was covalently bound to a triazatriangulene (TATA) platform via an acetylene unit and the resulting TATA-functionalised complex was deposited on a Au(111) surface. The corresponding self-assembled monolayer was characterised with scanning tunnelling microscopy (STM), X-ray photoelectron spectroscopy (XPS), and near-edge X-ray absorption fine structure (NEXAFS). The vibrational properties of the surface-adsorbed complexes were investigated with the help of infrared reflection absorption spectroscopy (IRRAS), and the frequency/intensity changes with respect to the bulk spectrum were analysed. A full vibrational analysis was performed with the help of DFT.

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.