936564-95-3Relevant academic research and scientific papers
Evaluation of the anti-hepatitis C virus effect of novel potent, selective, and orally bioavailable JNK and VEGFR kinase inhibitors
Raboisson, Pierre,Lenz, Oliver,Lin, Tse-I,Surleraux, Dominique,Chakravarty, Sarvajit,Scholliers, Annick,Vermeiren, Katrien,Delouvroy, Frederic,Verbinnen, Thierry,Simmen, Kenneth
, p. 1843 - 1849 (2007/10/03)
Screening of a focused library of TGF beta kinase inhibitors in the cellular HCV replicon model with luciferase read out yielded a number of low micromolar HCV inhibitors. Medicinal chemistry driven optimization resulted in the discovery of 4-[2-(5-bromo-
