936638-00-5

Upstream product

• 936637-99-9 ethyl 6-(hydroxymethyl)imidazo[1,2-a]pyridine-3-carboxylate 
• 1004550-09-7 ethyl 6-ethenylimidazo[1,2-a]pyridine-3-carboxylate 

Relevant academic research and scientific papers

THIOZOLIDINEDIONE DERIVATIVES AS P13 KINASE INHIBITORS

Invented is a method of inhibiting the activity/function of PB kinases using thiozolidinedione derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of thiozolidinedione derivatives.

NOVEL CHEMICAL COMPOUNDS

This invention relates to newly identified compounds for inhibiting YAK3 proteins and methods for treating diseases associated with the imbalance or inappropriate activity of YAK3 proteins.