93667-93-7

Upstream product

• 59626-32-3 3-(4-phenyl-1H-imidazol-1-yl)propanenitrile 
• 1048983-26-1 2-(3-(4-phenyl-1H-imidazol-1-yl)propyl)isoindoline-1,3-dione 
• 670-95-1 4-Phenylimidazole 

Downstream Products

• 93668-55-4 4-Chloro-N-[3-(4-phenyl-1H-imidazol-1-yl)propyl]-benzamide 
• 108060-72-6 5-Chloro-thiophene-2-carboxylic acid [3-(4-phenyl-imidazol-1-yl)-propyl]-amide 

Relevant academic research and scientific papers

Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase

Indoleamine 2,3-dioxygenase (IDO) is emerging as an important new therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression. With the goal of developing more potent IDO in

Method for inhibiting advanced glycosylation of proteins using aminosubstituted imidazoles

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging), Accordingly, a composition is disclosed which comprises 2-aminoimidazoles capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation, The method comprises contacting the target protein with the composition, Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.