936716-28-8Relevant academic research and scientific papers
Concise stereoselective total synthesis of (4 R, 6 R)-lactone moiety analog of mevinoline and compactin
Rao, D. Chandra,Reddy, D. Kumar,Chinnababu,Shekhar,Venkateswarlu
, p. 2980 - 2984 (2013/09/12)
A simple and highly efficient synthetic route has been developed for analogue of HMGCo A reductase inhibitor (1). The strategy utilizes S-Corey-Bakshi-Shibata (CBS) reduction, FeCl3-catalyzed C-H insertion of ethyl diazoacetate.
Total synthesis of a mevinic acid analog
Reddy, Thummalapally Srikanth,Reddy, Dorigondla Kumar,Narasimhulu, Manchala,Ramesh, Dasari,Venkateswarlu, Yenamandra
experimental part, p. 2158 - 2163 (2011/02/17)
Total synthesis of mevinic acid analog 1 has been achieved efficiently starting from chiral 2,3-O-isopropylidene-D-glyceraldehyde (2). The synthesis involves Mitsunobu reaction and Evans' intramolecular oxa-Michael syn-addition reactions as key steps. Cop
Stereoselective synthesis of a mevinic acid analogue
Sabitha, Gowravaram,Sudhakar,Srinivas,Yadav
, p. 705 - 708 (2007/12/29)
An efficient and versatile synthetic method for the stereoselective synthesis of a mevinic acid analogue is described. This approach uses a combination of a Cosford protocol with a catecholborane-mediated stereoselective reduction of acyclic P-hydroxy ket
